Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.68 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813547 | 1.00 | KLK5 (0.68) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6945132 | 1.00 | KLK5 (0.68) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6578313 | 0.90 | KLK5 (0.59) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1612669 | 0.90 | KLK5 (0.59) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3447452 | 0.89 | KLK5 (0.61) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5650822 | 0.89 | KLK5 (0.61) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL743357 | 0.89 | KLK5 (0.61) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15775826 | 0.89 | KLK5 (0.61) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL288838 | 0.89 | KLK5 (0.61) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7356486 | 0.89 | KLK5 (0.61) | KLK5PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| EP-0969000-B1 | Process for reducing alpha-amino ketones | KANEKA CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6255522-B1 | USING AS REDUCING AGENT A REACTION PRODUCT OF ORGANOALUMINUM COMPOUND, SULFONATE AND ALCOHOL | KANEKA CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6150567-A | REACTING CARBONYL COMPOUND WITH ORGANOALUMINUM COMPOUND TO FORM AN ALCOHOL COMPOUND | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0969000-A1 | PROCESS FOR REDUCING $G(a)-AMINO KETONES | KANEKA CORPORATION (JP) | 2000-01-05 | — | — | EP | disclosed |
| EP-0827943-A1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |