SCHEMBL694535

SCHEMBL694535

CC(C)C1=Cc2c(-c3cccc4ccccc34)ccc(-c3cccc4ccccc34)c2C1[Zr](C)(C)(=[SiH2])C1C(C(C)C)=Cc2c(-c3cccc4ccccc34)ccc(-c3cccc4ccccc34)c21

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX5 P09917 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL691235 0.99 AKR1C3 (0.32) AKR1C3AKR1C2NPC1MAPTRAB9A
SCHEMBL694261 0.88 AKR1C3 (0.31) AKR1C3AKR1C2NPC1MAPTRAB9A
Hydrochloric Acid SCHEMBL689522 0.87 AKR1C3 (0.30) AKR1C3AKR1C2
Hydrochloric Acid SCHEMBL2513912 0.85 MAPT (0.32) AKR1C3AKR1C2NPC1MAPTRAB9A
SCHEMBL693961 0.83 CA12 (0.32) PTPN1
Hydrochloric Acid SCHEMBL690284 0.82 CA12 (0.32) PTPN1
SCHEMBL689794 0.81
Hydrochloric Acid SCHEMBL1026091 0.81
Hydrochloric Acid SCHEMBL1026208 0.81
Hydrochloric Acid SCHEMBL690320 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203486-B9 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-08-01 EP claimed
EP-2203486-B1 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-02-29 EP claimed