Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101862 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL6949343 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL6949049 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL19101904 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL18772504 | 0.95 | TSHR (0.57) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL17762696 | 0.94 | TSHR (0.63) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL6144629 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL31105619 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL6145292 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1MEN1THRB | |
| SCHEMBL29283282 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850025-A | Method for dechlorinating polyvinyl chloride and preparing micromolecular chlorohydrocarbon | 华东理工大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-1143858-C | 6, 9-disubstituted 2- [ trans- (aminocyclohexyl) amino ] purines, compositions and uses thereof | ������ҩ������˾ | 2004-03-31 | — | — | CN | disclosed |
| US-6642231-B2 | Antineoplastic agents, treatment for neuronal injury and degeneration | AVENTIS PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |
| EP-1056744-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AVENTISUB II INC. | 2003-06-05 | — | — | US | disclosed |
| US-6479487-B1 | INHIBIT CYCLIN DEPENDENT KINASES, PARTICULARLY CDK-2; ANTIAPOPTOSIS AGENT; INHIBITS DEVELOPMENT OF NEOPLASMS | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| US-5972241-A | ELECTROOPTICAL APPLICATIONS, IN PARTICULAR THOSE WHICH REQUIRE COMPACT, ENERGY-EFFICIENT, VOLTAGE-CONTROLLED LIGHT VALVES, E.G., WATCHES AND COMPUTERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |
| US-5928562-A | HAVING EXTENDED HYDROCARBON ETHER GROUP ADJACENT TO A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP; LOW VISCOSITY; HIGH SPEED RESPONSE; BRIGHTNESS; COMMPATIBILITY; DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0746572-B1 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5827929-A | Functionalized initiators for anionic polymerization | FMC CORPORATION (US) | 1998-10-27 | — | — | US | disclosed |
| US-5792815-A | CONJUGATED POLYENE OR ALKENYL SUBSTITUTED ARYL HYDROCARBON POLYMERS; MOLDING MATERIALS | FMC CORPORATION (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997024377-A1 | FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| US-5621149-A | REACTING AN OMEGA-PROTECTED-1-HALOALKYL WITH AN ALKALI METAL DISPERSION IN AN INERT HYDROCARBON SOLVENT | FMC CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0746572-A4 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5600021-A | ORGANOMETALLIC COMPOUND CONTAINING ETHER GROUP | FMC CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0746572-A1 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORPORATION (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5567774-A | USING SODIUM, POTASSIUM, OR LITHIUM HYDROCARBYL ETHER COMPOUNDS AS INITIATORS | FMC CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| WO-1995022566-A1 | NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORPORATION (US) | 1995-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | CDK6, CDK5, CDK2 | TSHR 4411/4885ALDH1A1 2147/4885TDP1 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.