Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5718931 | 0.92 | DPP4 (0.42) | DPP4L3MBTL1ADRB1POLBSIRT5 | |
| SCHEMBL5792690 | 0.83 | DPP4 (0.64) | DPP4L3MBTL1POLBSIRT5ALDH1A1 | |
| SCHEMBL27623297 | 0.82 | DPP4 (0.49) | DPP4L3MBTL1ADRB1POLBSIRT5 | |
| SCHEMBL5719678 | 0.82 | DPP4 (0.68) | DPP4L3MBTL1ADRB1ALDH1A1KMT2A | |
| SCHEMBL2954897 | 0.81 | GAA (0.44) | L3MBTL1MEN1KMT2AMAPTGAA | |
| Trifluoroacetic Acid SCHEMBL5719494 | 0.76 | DPP4 (0.58) | DPP4L3MBTL1POLBSIRT5ALDH1A1 | |
| SCHEMBL13200001 | 0.76 | DPP4 (0.44) | DPP4L3MBTL1ADRB1ALDH1A1HTR2C | |
| SCHEMBL5789362 | 0.75 | DPP4 (0.61) | DPP4L3MBTL1ADRB1ALDH1A1HTR2C | |
| SCHEMBL5792563 | 0.75 | DPP4 (0.56) | DPP4L3MBTL1ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL2954275 | 0.73 | DPP4 (0.42) | DPP4L3MBTL1ADRB1ALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |