Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8669282 | 0.92 | SMN1; SMN2 (0.48) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| Fumaric Acid SCHEMBL8669278 | 0.92 | SMN1; SMN2 (0.48) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6947216 | 0.88 | SLC6A4 (0.55) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6948974 | 0.88 | DRD4 (0.45) | SLC6A4SMN1; SMN2KDM4EDRD4ALDH1A1 | |
| SCHEMBL6953959 | 0.82 | SLC6A4 (0.58) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6950204 | 0.81 | SLC6A4 (0.44) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| Fumaric Acid SCHEMBL8671237 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1LMNAKMT2APPARG | |
| Fumaric Acid SCHEMBL8671240 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1LMNAKMT2APPARG | |
| Hydrochloric Acid SCHEMBL6952909 | 0.81 | SLC6A4 (0.57) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8670829 | 0.80 | SLC6A4 (0.43) | SLC6A4SMN1; SMN2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709378-B1 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | AVENTIS PHARMA INC (US) | 2003-03-19 | — | — | EP | claimed |
| US-5696142-A | TREATING DEPRESSION, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-09 | — | — | US | claimed |
| EP-0709378-A2 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1996-05-01 | — | — | EP | claimed |