Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150127 | 0.94 | HDAC1 (0.42) | HDAC1HDAC6CXCR4FOLH1ADORA2A | |
| SCHEMBL6990541 | 0.91 | FOLH1 (0.37) | HDAC1HDAC6CXCR4FOLH1ADORA2A | |
| SCHEMBL6018818 | 0.91 | FOLH1 (0.37) | HDAC1HDAC6CXCR4FOLH1ADORA2A | |
| SCHEMBL6018347 | 0.91 | FOLH1 (0.37) | HDAC1HDAC6CXCR4FOLH1ADORA2A | |
| SCHEMBL6018408 | 0.90 | HDAC1 (0.38) | HDAC1HDAC6CXCR4ADORA2AITGAV | |
| SCHEMBL6681750 | 0.83 | HDAC1 (0.54) | HDAC1HDAC6CXCR4FOLH1ADORA2A | |
| SCHEMBL6018112 | 0.83 | HDAC1 (0.44) | HDAC1HDAC6CXCR4ADORA2ASLC40A1 | |
| SCHEMBL6018467 | 0.83 | CXCR4 (0.36) | HDAC1HDAC6CXCR4ADORA2AFNTA | |
| SCHEMBL6018159 | 0.83 | HDAC1 (0.41) | HDAC1HDAC6CXCR4ADORA2AFNTA | |
| SCHEMBL7150122 | 0.82 | HDAC1 (0.42) | HDAC1HDAC6CXCR4FOLH1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157818-A1 | Cxcr4-antagonistic drugs composed of nitrogen-containing compound | KUREHA CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157818-A1 | Cxcr4-antagonistic drugs composed of nitrogen-containing compound | CXCR4, CXCR1, CXCR2 | HDAC1 1092/4885HDAC6 1799/4885CXCR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.