Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945510 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1MAPTKDM5A | |
| SCHEMBL6061703 | 0.97 | TSHR (0.58) | TSHRALDH1A1TDP1MAPTKDM5A | |
| SCHEMBL1879456 | 0.94 | TSHR (0.63) | TSHRALDH1A1TDP1MAPTKDM5A | |
| SCHEMBL1884965 | 0.94 | TSHR (0.63) | TSHRALDH1A1TDP1MAPTKDM5A | |
| SCHEMBL1885053 | 0.94 | TSHR (0.63) | TSHRALDH1A1TDP1MAPTKDM5A | |
| SCHEMBL1883604 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1KDM5ALMNA | |
| SCHEMBL28337020 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1KDM5ALMNA | |
| SCHEMBL1885691 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1KDM5ALMNA | |
| SCHEMBL282416 | 0.92 | TSHR (0.56) | TSHRALDH1A1TDP1MAPTKDM5A | |
| Bromide SCHEMBL5550586 | 0.90 | TSHR (0.65) | TSHRALDH1A1TDP1KDM5ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896890-B | Polyimide slurry and polyimide film | 苏州尊尔光电科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-106832603-A | A kind of antibacterial atactic polypropylene water-feeding pipes and its production method | 北京崇高纳米科技有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-113896890-B | Polyimide slurry and polyimide film | 苏州尊尔光电科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-106832603-A | A kind of antibacterial atactic polypropylene water-feeding pipes and its production method | 北京崇高纳米科技有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-101010323-B | Bicyclononene derivatives as renin inhibitors | ACTELION PHARMACEUTICALS LTD | 2010-06-16 | — | — | CN | disclosed |
| CN-101010323-A | Bicyclononene derivatives as renin inhibitors | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-01 | — | — | CN | disclosed |
| US-6642231-B2 | Antineoplastic agents, treatment for neuronal injury and degeneration | AVENTIS PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |
| EP-1056744-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | AVENTISUB II INC. | 2003-06-05 | — | — | US | disclosed |
| US-6479487-B1 | INHIBIT CYCLIN DEPENDENT KINASES, PARTICULARLY CDK-2; ANTIAPOPTOSIS AGENT; INHIBITS DEVELOPMENT OF NEOPLASMS | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105098-A1 | 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines | CDK6, CDK5, CDK2 | TSHR 4411/4885ALDH1A1 2147/4885TDP1 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.