Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937085 | 0.92 | MAPT (0.67) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL6937260 | 0.90 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6937256 | 0.90 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6938854 | 0.86 | MAPT (0.65) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6941778 | 0.85 | MAPT (0.63) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6944586 | 0.84 | MAPT (0.55) | MAPTRAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL6944589 | 0.84 | MAPT (0.55) | MAPTRAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL6943780 | 0.84 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6943782 | 0.84 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6937019 | 0.84 | MAPT (0.54) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-B1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | claimed |