Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946598 | 0.84 | MEN1 (0.62) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6946674 | 0.79 | MAP2K1 (0.42) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6948269 | 0.78 | MEN1 (0.45) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6947497 | 0.75 | MEN1 (0.75) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6944419 | 0.74 | MAP2K1 (0.57) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6945033 | 0.73 | MAP2K1 (0.61) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL7122095 | 0.71 | MEN1 (0.44) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL5391354 | 0.70 | MEN1 (0.82) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6950416 | 0.70 | MEN1 (0.47) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6947374 | 0.69 | MEN1 (0.63) | MEN1KMT2ATDP1MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202724-B1 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | EP | claimed |