Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | MELK | Q14680 | 2/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947376 | 0.92 | MEN1 (0.38) | MEN1KMT2ATDP1DHODHMELK | |
| SCHEMBL6945840 | 0.84 | MEN1 (0.42) | MEN1KMT2ATDP1DHODHFTO | |
| SCHEMBL6941232 | 0.83 | MEN1 (0.41) | MEN1KMT2ATDP1DHODHFTO | |
| SCHEMBL6946757 | 0.79 | MEN1 (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL6944936 | 0.73 | MEN1 (0.67) | MEN1KMT2ATDP1 | |
| SCHEMBL6943774 | 0.69 | MEN1 (0.56) | MEN1KMT2ATDP1 | |
| SCHEMBL6948332 | 0.69 | MEN1 (0.42) | MEN1KMT2ATDP1DHODHFTO | |
| SCHEMBL6945160 | 0.67 | MEN1 (0.41) | MEN1KMT2ATDP1DHODHFTO | |
| SCHEMBL6944483 | 0.65 | MAP2K1 (0.57) | MEN1KMT2ATDP1 | |
| SCHEMBL5403672 | 0.64 | MEN1 (0.66) | MEN1KMT2ATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202724-B1 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | EP | claimed |