Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.48 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226141 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL177931 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL26107143 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL175425 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL14456385 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL5711897 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| Cyclohexane SCHEMBL3394348 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL11098596 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL14679380 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 | |
| SCHEMBL8089750 | 1.00 | EPHX1 (0.52) | EPHX1HPGDKMT2ASLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664249-B2 | Tetrasubstituted benzenes | ENVIVO PHARMACEUTICALS, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130165486-A1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| EP-1311292-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2001097861-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165486-A1 | TETRASUBSTITUTED BENZENES | BACE1, BACE2, PSEN1 | EPHX1 843/4885HPGD 1768/4885KMT2A 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.