Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167965 | 0.89 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AACHE | |
| SCHEMBL7167968 | 0.88 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2AMMP14 | |
| SCHEMBL5835749 | 0.81 | MAPT (0.73) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL6941718 | 0.80 | MAPT (0.57) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL3691462 | 0.79 | MAPT (0.64) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL3979891 | 0.79 | MAPT (0.64) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL8119079 | 0.79 | MAPT (0.64) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL5692166 | 0.78 | MAPT (0.62) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL4717364 | 0.76 | MAPT (0.56) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 | |
| Ethane SCHEMBL3302283 | 0.76 | MAPT (0.60) | MAPTALDH1A1L3MBTL1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968171-B1 | CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2003-10-08 | — | — | EP | disclosed |
| EP-0968171-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999003819-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-01-28 | — | — | WO | disclosed |