Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229669 | 0.84 | KMT2A (0.39) | KMT2AMEN1CYP11B1CYP11B2KIF11 | |
| SCHEMBL647893 | 0.83 | KMT2A (0.46) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL8188378 | 0.83 | KMT2A (0.46) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL1845371 | 0.83 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL6467815 | 0.83 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL5327785 | 0.83 | KMT2A (0.43) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL22832794 | 0.82 | KMT2A (0.40) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL8806580 | 0.80 | KMT2A (0.44) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL27544681 | 0.80 | KMT2A (0.41) | KMT2AMEN1CYP11B1CYP11B2KCNN4 | |
| SCHEMBL1528022 | 0.80 | KMT2A (0.44) | KMT2AMEN1CYP11B1CYP11B2KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311292-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2001097861-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |