Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 3/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979118 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10989313 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10979939 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10988273 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10985371 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10988758 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10981244 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10985255 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10980000 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA | |
| SCHEMBL10985932 | 1.00 | HRH3 (0.51) | HRH3RARBMEN1ALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854865-B1 | COMBINATORIAL SOLID PHASE SYNTHESIS OF A LIBRARY OF INDOLE DERIVATIVES | PHARMACIA ITALIA SPA (IT) | 2003-01-29 | — | — | EP | disclosed |
| US-5856496-A | Combinatorial solid phase synthesis of a library of indole derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-01-05 | — | — | US | disclosed |
| EP-0854865-A1 | COMBINATORIAL SOLID PHASE SYNTHESIS OF A LIBRARY OF INDOLE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997044319-A1 | COMBINATORIAL SOLID PHASE SYNTHESIS OF A LIBRARY OF INDOLE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-11-27 | — | — | WO | disclosed |