SCHEMBL6949382

SCHEMBL6949382

CCCCCn1nc(C(=O)NCCN2CCN(C)CC2)c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 8/20 0.57
CNR2 P34972 8/20 0.57
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
HTR3A P46098 1/20 0.46
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6944919 0.95 CNR1 (0.58) CNR1CNR2SMN1; SMN2MEN1KMT2A
SCHEMBL6950281 0.93 CNR1 (0.56) CNR1CNR2SMN1; SMN2KDM4EHSD17B10
SCHEMBL6955313 0.93 SMN1; SMN2 (0.51) CNR1CNR2SMN1; SMN2KDM4EALDH1A1
SCHEMBL6952236 0.90 CNR1 (0.54) CNR1CNR2KDM4EALDH1A1HTT
SCHEMBL6953804 0.90 CNR1 (0.56) CNR1CNR2SMN1; SMN2KDM4EHSD17B10
SCHEMBL6948551 0.89 CNR1 (0.53) CNR1CNR2SMN1; SMN2KDM4EALDH1A1
SCHEMBL6955741 0.88 MEN1 (0.53) CNR1CNR2SMN1; SMN2KDM4EALDH1A1
SCHEMBL6948507 0.87 CNR1 (0.51) CNR1CNR2SMN1; SMN2KDM4EHSD17B10
SCHEMBL6952257 0.85 CNR1 (0.53) CNR1CNR2SMN1; SMN2KDM4EALDH1A1
Hydrochloric Acid SCHEMBL7393720 0.84 KDM4E (0.53) CNR1CNR2SMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0829474-B1 INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP NISSHIN SEIFUN GROUP INC (JP) 2003-04-09 EP disclosed
US-6096746-A Indazole compound containing a monocyclic amine structure NISSHIN FLOUR MILLING CO., LTD. (JP) 2000-08-01 US disclosed
US-5945434-A TREATMENT OF GASTROINTESTINAL DISORDERS NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-08-31 US disclosed
EP-0829474-A1 INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP NISSHIN FLOUR MILLING CO., LTD. (JP) 1998-03-18 EP disclosed