⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956887 | 1.00 | — | — | |
| SCHEMBL99121 | 1.00 | — | — | |
| SCHEMBL115802 | 0.95 | — | — | |
| Fluoride SCHEMBL5958737 | 0.95 | — | — | |
| SCHEMBL8664532 | 0.95 | — | — | |
| SCHEMBL9260214 | 0.95 | — | — | |
| SCHEMBL9978847 | 0.84 | TSHR (0.33) | — | |
| Cyanate SCHEMBL27862407 | 0.79 | — | — | |
| Propane SCHEMBL28563973 | 0.74 | — | — | |
| SCHEMBL99031 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111556871-B | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-111491936-B | Macrocyclic compounds as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2017062879-A2 | DOSING REGIMENS | APELLIS PHARMACEUTICALS, INC. (US) | 2017-04-13 | — | — | WO | disclosed |
| US-20160301034-A1 | METHOD OF MANUFACTURING A DISPLAY DEVICE | MAGNOLIA WHITE CORPORATION (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160133937-A1 | NEGATIVE ELECTRODE MEMBRANE AND LITHIUM ION BATTTERY USING THE SAME | DONGGUAN AMPEREX TECHNOLOGY LIMITED (CN) | 2016-05-12 | — | — | US | disclosed |
| US-20160130299-A1 | TUBULYSIN ANALOGS AND METHODS OF MAKING AND USE | BRISTOL-MYERS SQUIBB COMPANY | 2016-05-12 | — | — | US | disclosed |
| US-20150141366-A1 | EFFECTIVE TREATMENT OF ESOPHOGEAL ADENOCARCINOMA USING TRICIRIBINE AND RELATED COMPOUNDS | UNIVERSITY OF SOUTH FLORIDA | 2015-05-21 | — | — | US | disclosed |
| US-20140363454-A1 | Antibody-Drug Conjugates, Compositions and Methods of Use | IGENICA BIOTHERAPEUTICS, INC. (US) | 2014-12-11 | — | — | US | disclosed |
| EP-2752203-A1 | Haemostatic material | Medtrade Products Ltd. (GB) | 2014-07-09 | — | — | EP | disclosed |
| EP-2692346-A1 | An antiviral 1-phenyl-2,5-dibenzimidazol-5-yl-pyrrolidine derivative | Abbvie Inc. (US) | 2014-02-05 | — | — | EP | disclosed |
| EP-1692286-B1 | Ice recrystallisation inhibition protein or antifreeze proteins from Deschampsia | AGRICULTURE VICTORIA SERV PTY (AU) | 2012-10-17 | — | — | EP | disclosed |
| US-7279134-B2 | Microfluidic devices with porous membranes for molecular sieving, metering, and separations | INTEL CORPORATION (US) | 2007-10-09 | — | — | US | disclosed |
| EP-1820504-A1 | IMINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-4450149-A | REASCTING AN ORGANIC BORANE WITH A RADIOACTIVE HALOMONOCHLORIDE AND A MILD OXIDIZER; RADIOLOGY | RESEARCH CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |