Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8670830 | 0.99 | SLC6A4 (0.59) | SLC6A4HSD17B10ALOX15TBXA2RSIGMAR1 | |
| SCHEMBL6947048 | 0.88 | SLC6A4 (0.58) | SLC6A4HSD17B10TBXA2RKDM4ETP53 | |
| Hydrochloric Acid SCHEMBL6950832 | 0.87 | SLC6A4 (0.57) | SLC6A4TBXA2RKDM4ETP53ALDH1A1 | |
| SCHEMBL2434453 | 0.85 | DRD4 (0.49) | SLC6A4HSD17B10ALOX15SIGMAR1TP53 | |
| SCHEMBL7977340 | 0.85 | DRD4 (0.49) | SLC6A4HSD17B10ALOX15SIGMAR1TP53 | |
| SCHEMBL2434454 | 0.85 | DRD4 (0.49) | SLC6A4HSD17B10ALOX15SIGMAR1TP53 | |
| SCHEMBL6950846 | 0.84 | SLC6A4 (0.58) | SLC6A4TBXA2RSIGMAR1LMNAMEN1 | |
| SCHEMBL6952895 | 0.84 | TBXA2R (0.59) | SLC6A4TBXA2RLMNAMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL8667500 | 0.83 | SLC6A4 (0.57) | SLC6A4TBXA2RSIGMAR1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8669217 | 0.83 | TBXA2R (0.58) | SLC6A4TBXA2RLMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709378-B1 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | AVENTIS PHARMA INC (US) | 2003-03-19 | — | — | EP | claimed |
| US-5696142-A | TREATING DEPRESSION, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-09 | — | — | US | claimed |
| EP-0709378-A2 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1996-05-01 | — | — | EP | claimed |