Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951903 | 1.00 | RECQL (0.43) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL21797068 | 0.83 | HPGD (0.43) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL18399262 | 0.83 | HPGD (0.43) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL25343328 | 0.81 | HPGD (0.47) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL25289080 | 0.81 | HPGD (0.47) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL23692790 | 0.81 | HPGD (0.47) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL16961994 | 0.81 | HPGD (0.47) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL8114809 | 0.81 | HPGD (0.47) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL24969958 | 0.78 | HPGD (0.51) | RECQLGPR119HPGDUSP2SMN1; SMN2 | |
| SCHEMBL16661889 | 0.78 | HPGD (0.51) | RECQLGPR119HPGDUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |