Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | NPC1 | O15118 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | PKM | P14618 | 2/20 | 0.81 |
| ▸ | ATM | Q13315 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | MIF | P14174 | 5/20 | 0.68 |
| ▸ | CASP3 | P42574 | 3/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545183 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8545182 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12306186 | 0.87 | MAPT (0.74) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3135826 | 0.87 | MAPT (0.74) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3135832 | 0.87 | MAPT (0.74) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29546016 | 0.87 | MAPT (0.74) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5724855 | 0.83 | MIF (0.81) | MAPTLMNASMN1; SMN2ALDH1A1MIF | |
| SCHEMBL17077383 | 0.82 | EGFR (0.89) | MIFMAOBEGFRXDHNFE2L2 | |
| SCHEMBL17077385 | 0.82 | EGFR (0.89) | MIFMAOBEGFRXDHNFE2L2 | |
| SCHEMBL17077354 | 0.82 | EGFR (0.86) | LMNASMN1; SMN2EGFRXDHNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023063-B1 | INDENO[1,2-c], NAPHTHO[1,2-c]- AND BENZO[6,7]CYCLOHEPTA[1,2-c]PYRAZOLE DERIVATIVES | ABBOTT GMBH & CO KG (DE) | 2003-09-10 | — | — | EP | disclosed |