SCHEMBL69553

SCHEMBL69553

COC(=O)c1ccccc1C=Cc1ccccc1C(=O)OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.60
TSHR P16473 2/20 0.59
LMNA P02545 2/20 0.59
ALDH1A1 P00352 2/20 0.57
HSD17B10 Q99714 2/20 0.57
CFTR P13569 1/20 0.57
KDM4E B2RXH2 2/20 0.55
POLB P06746 2/20 0.55
ATM Q13315 1/20 0.55
KMT2A Q03164 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
SLC6A3 Q01959 4/20 0.49
MYC P01106 1/20 0.49
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69552 1.00 BACE1 (0.60) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL30423635 0.91 BACE1 (0.61) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL2658197 0.91 BACE1 (0.61) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL29227737 0.91 BACE1 (0.61) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL2658196 0.91 BACE1 (0.61) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL12678685 0.90 BACE1 (0.56) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL28658058 0.90 BACE1 (0.56) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL9000475 0.89 BACE1 (0.52) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL9000471 0.89 BACE1 (0.52) BACE1TSHRLMNAALDH1A1HSD17B10
SCHEMBL9846778 0.89 BACE1 (0.55) BACE1TSHRLMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 BACE1 4856/4885TSHR 3263/4885LMNA 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.