Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651041 | 0.92 | MAPT (0.52) | PHGDHCYP3A4MEN1PKMKMT2A | |
| SCHEMBL6960739 | 0.91 | PHGDH (0.55) | PHGDHCYP3A4MEN1PKMKMT2A | |
| SCHEMBL6960822 | 0.90 | KMT2A (0.42) | PHGDHKMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL6657881 | 0.86 | PHGDH (0.56) | PHGDHCYP3A4MEN1PKMKMT2A | |
| SCHEMBL6675114 | 0.86 | PHGDH (0.38) | PHGDHCYP3A4MEN1PKMKMT2A | |
| SCHEMBL7084407 | 0.85 | MAPT (0.53) | PHGDHCYP3A4MEN1PKMKMT2A | |
| SCHEMBL6653887 | 0.84 | PHGDH (0.52) | PHGDHCYP3A4MEN1PKMKMT2A | |
| SCHEMBL6653788 | 0.83 | MAPT (0.57) | PHGDHCYP3A4MAPTGAACYP2C19 | |
| SCHEMBL6651629 | 0.83 | MAPT (0.57) | PHGDHCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL6651807 | 0.82 | MAPT (0.48) | PHGDHCYP3A4MEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |