Sugi Predict

Sugi Predict / Compounds / SCHEMBL6957019

SCHEMBL6957019

SCHEMBL6957019

CC(C)(C)CN1C(=O)[C@@H](CC(=O)NCC(=O)O)O[C@H](c2ccccc2Cl)c2cc(Cl)ccc21

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FDFT1 P37268 17/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9057751 0.90 FDFT1 (0.64) FDFT1
SCHEMBL6958743 0.90 FDFT1 (0.64) FDFT1
SCHEMBL6958739 0.90 FDFT1 (0.64) FDFT1
SCHEMBL4105096 0.90 FDFT1 (0.64) FDFT1
SCHEMBL6951678 0.90 FDFT1 (0.77) FDFT1
SCHEMBL6951670 0.90 FDFT1 (0.77) FDFT1
SCHEMBL7083662 0.90 FDFT1 (0.54) FDFT1
SCHEMBL6963107 0.89 FDFT1 (0.54) FDFT1
SCHEMBL6963109 0.89 FDFT1 (0.54) FDFT1
SCHEMBL6963116 0.89 FDFT1 (0.54) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0567026-B1 4,1-Benzoxazepin derivatives as squalene synthase inhibitors and their use in the treatment of hypercholesteremia and as fungicides TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-03-26 — — EP disclosed
EP-0949238-A1 SUBSTITUTED PROPIONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-10-13 — — EP disclosed
EP-0567026-A1 4,1-Benzoxazepin derivatives as squalene synthase inhibitors and their use in the treatment of hypercholesteremia and as fungicides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-27 — — EP disclosed