Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959991 | 0.97 | S1PR1 (0.46) | S1PR1FFAR1KDM1AMAOAMAOB | |
| SCHEMBL6951315 | 0.93 | PDE4B (0.41) | KDM4EALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL6954512 | 0.92 | PDE4B (0.43) | S1PR1KDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL7076319 | 0.91 | KDM1A (0.40) | S1PR1KDM1AMAOAMAOBKDM4E | |
| SCHEMBL7074937 | 0.91 | MEN1 (0.41) | KDM1AKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL6955072 | 0.90 | KDM4E (0.42) | KDM1AMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL6959509 | 0.90 | NPC1 (0.44) | KDM1AMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL6960145 | 0.88 | KDM4E (0.36) | S1PR1KDM1AMAOAMAOBKDM4E | |
| SCHEMBL6958492 | 0.88 | S1PR1 (0.48) | S1PR1FFAR1KDM1AMAOAMAOB | |
| SCHEMBL6949756 | 0.86 | MEN1 (0.37) | S1PR1KDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |