Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957425 | 1.00 | KMT2A (0.36) | KMT2AGAAKDM4EMEN1MAOA | |
| SCHEMBL6965565 | 0.94 | KMT2A (0.35) | KMT2AGAAKDM4EMEN1MAOA | |
| SCHEMBL6965047 | 0.94 | KMT2A (0.35) | KMT2AGAAKDM4EMEN1MAOA | |
| SCHEMBL6958023 | 0.90 | KMT2A (0.35) | KMT2AMEN1MAPTSMN1; SMN2CA2 | |
| SCHEMBL6958026 | 0.90 | KMT2A (0.35) | KMT2AMEN1MAPTSMN1; SMN2CA2 | |
| SCHEMBL6961412 | 0.88 | SMN1; SMN2 (0.37) | KMT2AMAPTSMN1; SMN2KCNH3ESR1 | |
| SCHEMBL6965486 | 0.87 | KMT2A (0.37) | KMT2AMEN1MAPTSMN1; SMN2CA2 | |
| SCHEMBL6962863 | 0.85 | KMT2A (0.38) | KMT2AKDM4EMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6956125 | 0.85 | KMT2A (0.35) | KMT2AMAPTSMN1; SMN2KCNH3EGFR | |
| SCHEMBL6962957 | 0.85 | KMT2A (0.35) | KMT2AMEN1MAPTSMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |