Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959003 | 0.93 | TP53 (0.41) | TTRTP53MAPTNPSR1 | |
| SCHEMBL6962207 | 0.93 | SMN1; SMN2 (0.38) | CCNE1CDK2TP53KDM4ENPSR1 | |
| SCHEMBL6961412 | 0.93 | SMN1; SMN2 (0.37) | CCNE1CDK2TTRTP53MAPT | |
| SCHEMBL6955562 | 0.91 | SRD5A1 (0.37) | GRIN2C | |
| SCHEMBL6958506 | 0.89 | SMN1; SMN2 (0.39) | CCNE1CDK2TP53MAPTKDM4E | |
| SCHEMBL6958156 | 0.89 | CDC7 (0.35) | TTRTP53MAPTKDM4EALDH1A1 | |
| SCHEMBL6957084 | 0.89 | KMT2A (0.33) | CCNE1CDK2TP53MAPTNPSR1 | |
| SCHEMBL6962863 | 0.88 | KMT2A (0.38) | CCNE1CDK2MAPTKDM4ENPSR1 | |
| SCHEMBL6957761 | 0.88 | TP53 (0.40) | CCNE1CDK2TTRTP53MAPT | |
| SCHEMBL6956125 | 0.88 | KMT2A (0.35) | CCNE1CDK2TP53MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |