Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87638 | 0.78 | TDP1 (0.48) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL8972017 | 0.76 | CYP1A2 (0.52) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL5694593 | 0.72 | IAPP (0.55) | LMNAMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9341839 | 0.71 | MAPT (0.69) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9341842 | 0.71 | MAPT (0.69) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9998235 | 0.69 | MAPT (0.53) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9998233 | 0.69 | MAPT (0.53) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL502894 | 0.69 | AKR1C3 (0.53) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL502895 | 0.69 | AKR1C3 (0.53) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9997472 | 0.68 | KMT2A (0.45) | LMNAMAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |