SCHEMBL6958111

SCHEMBL6958111

Cc1nc(C(C)C)c(CO)c(-c2ccc(F)cc2)c1C=[N+](O)C#N

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9284471 0.79 GCGR (0.63) GCGR
SCHEMBL9284473 0.79 GCGR (0.63) GCGR
SCHEMBL6958359 0.78 GCGR (0.64) GCGR
SCHEMBL8949777 0.78 GCGR (0.74) GCGR
SCHEMBL2648867 0.76 GCGR (0.63) GCGR
SCHEMBL2648869 0.76 GCGR (0.63) GCGR
SCHEMBL8949822 0.75 GCGR (0.88) GCGR
SCHEMBL2648452 0.73 GCGR (1.00) GCGR
SCHEMBL2656279 0.72 GCGR (1.00) GCGR
SCHEMBL2647176 0.72 GCGR (0.75) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325130-B1 Substituted pyridines BAYER AG (DE) 2003-11-05 EP disclosed
EP-1123925-A1 Process for preparation of substituted pyridines BAYER AG (DE) 2001-08-16 EP disclosed
EP-1123924-A1 Substituted pyridines as HMG-COA reductase inhibitors BAYER AG (DE) 2001-08-16 EP disclosed
EP-0325130-A2 Substituted pyridines BAYER AG (DE) 1989-07-26 EP disclosed