Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.59 |
| ▸ | PPARA | Q07869 | 15/20 | 0.59 |
| ▸ | PPARD | Q03181 | 8/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959020 | 0.95 | PPARG (0.60) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL6958121 | 0.91 | FFAR1 (0.62) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL6964987 | 0.89 | FFAR1 (0.62) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL8846257 | 0.88 | FFAR1 (0.61) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL6971037 | 0.86 | FFAR1 (0.63) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL5915216 | 0.83 | PPARG (0.68) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL8845978 | 0.83 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL6969645 | 0.82 | PPARG (0.67) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL6382155 | 0.82 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL6957652 | 0.82 | FFAR1 (0.51) | PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |