Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959704 | 1.00 | MEN1 (0.64) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL6960322 | 0.77 | UGT2B7 (0.47) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL27878044 | 0.77 | UGT2B7 (0.47) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL6568105 | 0.76 | TSHR (0.46) | MEN1KMT2AATMCYP2D6CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27969960 | 0.76 | UGT2B7 (0.46) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL11878770 | 0.75 | UGT2B7 (0.50) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL11878781 | 0.75 | UGT2B7 (0.50) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL11881336 | 0.74 | UGT2B7 (0.48) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL29817405 | 0.74 | UGT2B7 (0.63) | MEN1KMT2AATMUGT2B7CYP2D6 | |
| SCHEMBL6191864 | 0.74 | UGT2B7 (0.63) | MEN1KMT2AATMUGT2B7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974584-B1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6420375-B1 | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |