Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 7/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965356 | 0.94 | — | — | |
| SCHEMBL6973301 | 0.82 | — | — | |
| SCHEMBL14880140 | 0.81 | HDAC2 (1.00) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL6959845 | 0.79 | HDAC2 (0.68) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5479808 | 0.79 | HDAC2 (0.96) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5521547 | 0.79 | HDAC2 (0.68) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL10986673 | 0.78 | HDAC2 (0.66) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5517039 | 0.78 | HDAC2 (0.66) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5513200 | 0.78 | HDAC2 (0.66) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL5517044 | 0.78 | HDAC2 (0.66) | HDAC2HDAC4HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |