SCHEMBL6959839

SCHEMBL6959839

CCCOP([O])(=O)OCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TSHR P16473 3/20 0.38
LPAR3 Q9UBY5 4/20 0.37
LPAR1 Q92633 2/20 0.37
LPAR2 Q9HBW0 2/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HMGCR P04035 1/20 0.34
LMNA P02545 1/20 0.33
ESR1 P03372 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CDC25A P30304 1/20 0.33
AGTR1 P30556 1/20 0.33
AKT1 P31749 1/20 0.33
ADRA1A P35348 1/20 0.33
KCNH2 Q12809 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17333509 0.84 CYP3A4 (0.52) CYP3A4MEN1KMT2ATSHRLPAR3
SCHEMBL2866705 0.82 CYP3A4 (0.67) CYP3A4TSHRLPAR3LPAR1LPAR2
SCHEMBL31023525 0.81 CYP3A4 (0.65) CYP3A4MEN1KMT2ATSHRLPAR3
SCHEMBL3261925 0.80 LPAR3 (0.60) CYP3A4TSHRLPAR3LPAR1LPAR2
SCHEMBL17333526 0.80 CYP3A4 (0.48) CYP3A4MEN1KMT2ATSHRLPAR3
SCHEMBL6959795 0.78 LPAR3 (0.64) CYP3A4LPAR3LPAR1LPAR2LMNA
SCHEMBL55462 0.78 LPAR3 (0.64) CYP3A4LPAR3LPAR1LPAR2LMNA
SCHEMBL104844 0.78 CYP3A4 (0.68) CYP3A4MEN1KMT2ATSHRLPAR3
SCHEMBL9261026 0.77
SCHEMBL10987709 0.77 CYP3A4 (0.40) CYP3A4MEN1KMT2ATSHRLPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439252-B2 Electrolyte solution for electrochemical device, and electrochemical device FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-08 US disclosed
US-20150364792-A1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICE, AND ELECTROCHEMICAL DEVICE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-17 US disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
EP-0664281-B1 ISOCARBACYCLIN WITH MODIFIED alpha(a)-CHAIN AND PROCESS FOR PRODUCING THE SAME TEIJIN LTD (JP) 1997-05-28 EP disclosed
EP-0664281-A1 ISOCARBACYCLIN WITH MODIFIED $g(a)-CHAIN AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1995-07-26 EP disclosed
US-5391564-A E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents SANKYO COMPANY, LIMITED (JP) 1995-02-21 US disclosed
US-5352689-A Rhizoxin derivatives and their use as anti-tumor agents SANKYO COMPANY, LIMITED (JP) 1994-10-04 US disclosed
EP-0350315-B1 RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS SANKYO COMPANY LIMITED (JP) 1993-06-16 EP disclosed
EP-0350315-A1 Rhizoxin derivates and their use as anti-tumor agents SANKYO COMPANY LIMITED (JP) 1990-01-10 EP disclosed
US-4851535-A 2-(5-FLUORONICOTINOYL)ACETIC ACID DERIVATIVES, ANTIBACTERIAL 1-ARYL-1,4-DIHYDRO-4-OXONAPHTHYRIDINES TOYAMA CHEMICAL CO., LTD. (JP) 1989-07-25 US disclosed
US-4704459-A VILSMEIER REAGENT TOYAMA CHEMICAL CO., LTD. (JP) 1987-11-03 US disclosed