Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 11/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960434 | 1.00 | STK17B (0.74) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6966601 | 0.91 | STK17B (0.74) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| 3',4'-Dimethoxy-Aurone SCHEMBL21082559 | 0.85 | STK17B (1.00) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| 3',4'-Dimethoxy-Aurone SCHEMBL29898356 | 0.85 | STK17B (1.00) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19462965 | 0.84 | STK17B (1.00) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19462865 | 0.82 | STK17B (1.00) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29537683 | 0.82 | STK17B (1.00) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10921543 | 0.81 | STK17B (0.74) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12696424 | 0.80 | STK17B (0.79) | STK17BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14501946 | 0.79 | MEN1 (0.72) | STK17BHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |