Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 9/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957652 | 0.85 | FFAR1 (0.51) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6958121 | 0.85 | FFAR1 (0.62) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6963929 | 0.84 | PPARG (0.46) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6964987 | 0.83 | FFAR1 (0.62) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL8845954 | 0.83 | FFAR1 (0.50) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL8846257 | 0.82 | FFAR1 (0.61) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6967639 | 0.81 | FFAR1 (0.48) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6971037 | 0.80 | FFAR1 (0.63) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6052350 | 0.77 | FFAR1 (0.44) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6052344 | 0.77 | PPARG (0.60) | FFAR1PPARGPPARAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | claimed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | claimed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | claimed |