Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641579 | 0.92 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6960529 | 0.92 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL6953873 | 0.92 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL6641926 | 0.91 | EDNRA (0.85) | EDNRAEDNRB | |
| SCHEMBL6637541 | 0.91 | EDNRA (0.85) | EDNRAEDNRB | |
| SCHEMBL6641023 | 0.91 | EDNRA (0.85) | EDNRAEDNRB | |
| SCHEMBL6639397 | 0.90 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL6641874 | 0.90 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL6638815 | 0.89 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL6638782 | 0.89 | EDNRA (0.88) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702012-B1 | Substituted isoxazole sulfonamides and their use as endothelin antagonists | BRISTOL MYERS SQUIBB CO (US) | 2003-10-15 | — | — | EP | claimed |
| EP-0702012-B1 | Substituted isoxazole sulfonamides and their use as endothelin antagonists | BRISTOL MYERS SQUIBB CO (US) | 2003-10-15 | — | — | EP | disclosed |