Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.86 |
| ▸ | PDE4A | P27815 | 18/20 | 0.86 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.86 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050561 | 0.92 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6942657 | 0.91 | PDE4A (0.71) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6836442 | 0.89 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8333880 | 0.88 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5723021 | 0.84 | PDE4D (0.77) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7055210 | 0.83 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6959410 | 0.83 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6837997 | 0.83 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7919048 | 0.83 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6837701 | 0.81 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1029860-B1 | BENZOFURAN DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| EP-1029860-A1 | BENZOFURAN DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-08-23 | — | — | EP | disclosed |