Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | F2 | P00734 | 10/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.61 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6954511 | 0.99 | F10 (0.70) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6956700 | 0.91 | F10 (0.72) | F10KCNH2F2PRSS1PLG | |
| SCHEMBL13703904 | 0.90 | F10 (0.73) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6957911 | 0.90 | F10 (0.72) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6952037 | 0.90 | F10 (0.72) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6960282 | 0.90 | F10 (0.71) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6960585 | 0.89 | F10 (0.74) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6954228 | 0.89 | F10 (0.70) | F10KCNH2F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL6955500 | 0.89 | F10 (0.75) | F10KCNH2F2PRSS1PLG | |
| SCHEMBL6951067 | 0.88 | F10 (0.60) | F10KCNH2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798295-B1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |