SCHEMBL6961920

SCHEMBL6961920

CCOC(=O)Oc1c(C(C)C)nc(C)c(CO)c1-c1ccc(F)cc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6953892 0.92 GCGR (0.61) GCGR
SCHEMBL6961105 0.89 GCGR (0.50) GCGR
SCHEMBL9410045 0.89 GCGR (0.50) GCGR
SCHEMBL6949857 0.86 PRKAA2 (0.47) GCGR
SCHEMBL6962775 0.85 GCGR (0.48) GCGR
SCHEMBL6958555 0.84 GCGR (0.61) GCGR
SCHEMBL6963303 0.84 GCGR (0.50) GCGR
SCHEMBL2649345 0.82 GCGR (0.67) GCGR
SCHEMBL8953339 0.81 GCGR (0.50) GCGR
SCHEMBL6957684 0.80 GCGR (0.46) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325130-B1 Substituted pyridines BAYER AG (DE) 2003-11-05 EP disclosed
EP-1123925-A1 Process for preparation of substituted pyridines BAYER AG (DE) 2001-08-16 EP disclosed
EP-1123924-A1 Substituted pyridines as HMG-COA reductase inhibitors BAYER AG (DE) 2001-08-16 EP disclosed
EP-0325130-A2 Substituted pyridines BAYER AG (DE) 1989-07-26 EP disclosed