⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963830 | 1.00 | — | — | |
| SCHEMBL10660255 | 1.00 | — | — | |
| SCHEMBL4098581 | 0.84 | BRD4 (0.34) | — | |
| SCHEMBL5156976 | 0.84 | BRD4 (0.34) | — | |
| SCHEMBL11167060 | 0.81 | TP53 (0.33) | — | |
| SCHEMBL9782561 | 0.81 | — | — | |
| SCHEMBL11005101 | 0.81 | — | — | |
| SCHEMBL11066672 | 0.80 | — | — | |
| SCHEMBL9782696 | 0.80 | — | — | |
| SCHEMBL10965368 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |