Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | MMP8 | P22894 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7955825 | 0.92 | CYP2D6 (0.55) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL24322367 | 0.91 | POLB (0.54) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL11710494 | 0.91 | POLB (0.54) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| Hydrochloric Acid SCHEMBL11100779 | 0.85 | CYP2D6 (0.63) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL7955831 | 0.82 | CYP2D6 (0.50) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL10627851 | 0.81 | KMT2A (0.77) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL10611159 | 0.81 | KMT2A (0.77) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL10423181 | 0.81 | KMT2A (0.77) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL10626768 | 0.81 | DPP7 (0.63) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL10626773 | 0.81 | DPP7 (0.63) | CYP2D6CYP2C9CYP2C19KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | CYP2D6 4712/4885CYP2C9 4549/4885CYP2C19 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.