Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.66 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585516 | 0.84 | CES1 (0.68) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL2586906 | 0.83 | CES1 (0.66) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL17938162 | 0.81 | CES1 (0.63) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL5580542 | 0.81 | CES1 (0.69) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL1454439 | 0.81 | CES1 (0.63) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL1454436 | 0.81 | CES1 (0.63) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL10714724 | 0.81 | CES1 (0.63) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL10437570 | 0.81 | CES1 (0.63) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL21610298 | 0.81 | CES1 (0.63) | CES1KCNN4KMT2AMAPTCYP2C19 | |
| SCHEMBL1679763 | 0.79 | CES1 (1.00) | CES1KCNN4KMT2AMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |