Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.66 |
| ▸ | OXTR | P30559 | 2/20 | 0.66 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968384 | 0.91 | AVPR2 (0.71) | AVPR2OXTRAVPR1A | |
| SCHEMBL6971659 | 0.89 | AVPR2 (0.74) | AVPR2OXTRAVPR1A | |
| SCHEMBL6959843 | 0.88 | AVPR2 (0.69) | AVPR2OXTRAVPR1A | |
| SCHEMBL12433961 | 0.86 | AVPR1A (0.65) | AVPR2OXTRAVPR1A | |
| SCHEMBL6971391 | 0.85 | AVPR2 (0.79) | AVPR2OXTRAVPR1A | |
| SCHEMBL6971833 | 0.85 | AVPR2 (0.79) | AVPR2OXTRAVPR1A | |
| SCHEMBL6963965 | 0.84 | AVPR2 (0.72) | AVPR2OXTRAVPR1A | |
| SCHEMBL6972321 | 0.81 | AVPR2 (0.71) | AVPR2OXTRAVPR1A | |
| SCHEMBL6970320 | 0.81 | AVPR2 (0.76) | AVPR2OXTRAVPR1A | |
| SCHEMBL6972323 | 0.81 | AVPR2 (0.80) | AVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| CN-1098406-A | New benzamide derivatives and method for making thereof and the pharmaceutical composition that contains them | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-02-08 | — | — | CN | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |