Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.57 |
| ▸ | PPARA | Q07869 | 16/20 | 0.57 |
| ▸ | PPARD | Q03181 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964537 | 1.00 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL6971178 | 0.95 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL6971180 | 0.95 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL27385540 | 0.86 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL6970285 | 0.84 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL14002819 | 0.84 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL6971842 | 0.82 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL6971832 | 0.82 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL14382157 | 0.81 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL12652544 | 0.81 | PPARG (0.69) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |