Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6964668 | 0.98 | CNR1 (0.43) | CNR1CNR2S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL6960783 | 0.93 | PPARG (0.39) | CNR1CNR2S1PR2S1PR1S1PR3 | |
| SCHEMBL6963865 | 0.91 | SCN2A (0.43) | S1PR2S1PR1S1PR3LPAR2SCN2A | |
| SCHEMBL6966157 | 0.90 | SCN2A (0.39) | CNR1CNR2S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL6964504 | 0.89 | SCN2A (0.39) | CNR1CNR2S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL6960938 | 0.88 | PPARG (0.40) | SCN2APPARGPPARAGSRFFAR1 | |
| Hydrochloric Acid SCHEMBL6964752 | 0.88 | PPARG (0.40) | SCN2APPARGPPARAGSRFFAR1 | |
| Hydrochloric Acid SCHEMBL6964746 | 0.88 | PPARG (0.40) | SCN2APPARGPPARAGSRFFAR1 | |
| SCHEMBL6960245 | 0.85 | PPARG (0.37) | PPARGPPARAGAAFFAR1 | |
| SCHEMBL6955574 | 0.84 | PPARG (0.38) | S1PR2S1PR1S1PR3LPAR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971709-B1 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | LILLY CO ELI (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-0908454-A2 | Oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents | ELI LILLY AND COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |