Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979348 | 1.00 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6978943 | 1.00 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6964675 | 1.00 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6979343 | 1.00 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6966413 | 1.00 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7107943 | 0.95 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7107942 | 0.95 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6966512 | 0.94 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6974983 | 0.94 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6974977 | 0.94 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821719-B1 | LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 2003-01-02 | — | — | EP | disclosed |