⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875297 | 0.71 | — | — | |
| SCHEMBL8599442 | 0.70 | — | — | |
| Bromide SCHEMBL27301681 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL152475 | 0.67 | — | — | |
| SCHEMBL6953756 | 0.65 | — | — | |
| SCHEMBL6959248 | 0.65 | — | — | |
| SCHEMBL1653708 | 0.63 | — | — | |
| SCHEMBL28114469 | 0.63 | TSHR (0.30) | — | |
| SCHEMBL1653693 | 0.61 | — | — | |
| SCHEMBL1652887 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |