Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 20/20 | 0.49 |
| ▸ | EDNRB | P24530 | 15/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965095 | 0.90 | EDNRA (0.57) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6965740 | 0.89 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL6965374 | 0.89 | EDNRA (0.41) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6972701 | 0.88 | EDNRA (0.60) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6973418 | 0.86 | EDNRA (0.53) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6974941 | 0.84 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL7948246 | 0.83 | EDNRA (0.53) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL7503704 | 0.83 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL6962526 | 0.82 | EDNRA (0.61) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6967820 | 0.81 | EDNRA (0.48) | EDNRAEDNRBABCC3ABCC4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799209-B1 | SULFONAMIDES | HOFFMANN LA ROCHE (CH) | 2003-08-06 | — | — | EP | claimed |