Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.58 |
| ▸ | PPARA | Q07869 | 19/20 | 0.58 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965423 | 1.00 | PPARG (0.58) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL5622683 | 0.90 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5622684 | 0.90 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL6965649 | 0.86 | HPGD (0.45) | PPARGPPARAPPARD | |
| SCHEMBL6965652 | 0.86 | HPGD (0.45) | PPARGPPARAPPARD | |
| SCHEMBL7618958 | 0.86 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL7617150 | 0.85 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6966778 | 0.80 | PPARG (0.52) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL6966781 | 0.80 | PPARG (0.52) | PPARGPPARAPPARDPTPN1 | |
| SCHEMBL5049259 | 0.79 | PPARG (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970077-B1 | IMPROVED METHOD FOR PRODUCING THIAZOLIDINEDIONES, AND NEW THIAZOLIDINEDIONES | ROCHE DIAGNOSTICS GMBH (DE) | 2003-05-14 | — | — | EP | disclosed |
| EP-0970077-A1 | IMPROVED METHOD FOR PRODUCING THIAZOLIDINEDIONES, AND NEW THIAZOLIDINEDIONES | Roche Diagnostics GmbH (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998042704-A1 | IMPROVED METHOD FOR PRODUCING THIAZOLIDINEDIONES, AND NEW THIAZOLIDINEDIONES | ROCHE DIAGNOSTICS GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |