Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | STK17B | O94768 | 1/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965599 | 1.00 | MAOB (0.77) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6971467 | 0.95 | MAOB (0.70) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6971471 | 0.95 | MAOB (0.70) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6967163 | 0.94 | MAOB (0.71) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6969307 | 0.94 | MAOB (0.71) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6969312 | 0.94 | MAOB (0.71) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6967159 | 0.94 | MAOB (0.71) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6966211 | 0.85 | MEN1 (0.68) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL6966205 | 0.85 | MEN1 (0.68) | MAOBMEN1KMT2ARECQLKDM4E | |
| SCHEMBL30509615 | 0.82 | MAOB (0.53) | MAOBMEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |