Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125161 | 0.94 | — | — | |
| SCHEMBL7587889 | 0.94 | GRIA1 (0.35) | TP53 | |
| Potassium Ion SCHEMBL18008192 | 0.94 | — | — | |
| Lithium Ion SCHEMBL18008587 | 0.94 | — | — | |
| Tetrylammonium SCHEMBL18008434 | 0.82 | TSHR (0.38) | — | |
| SCHEMBL10711382 | 0.75 | KDM4E (0.35) | TP53 | |
| SCHEMBL1668223 | 0.75 | — | — | |
| SCHEMBL6965273 | 0.75 | — | — | |
| Lithium Ion SCHEMBL4299560 | 0.71 | — | — | |
| SCHEMBL1138618 | 0.71 | TSHR (0.33) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | claimed |