Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 10/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960868 | 0.89 | MAOB (0.52) | CYP3A4MAOBPTPN1PPARGPPARA | |
| SCHEMBL27383098 | 0.82 | MAOB (0.52) | CYP3A4MAOBALOX5HPGDS | |
| SCHEMBL6967080 | 0.80 | MAOB (0.58) | CYP3A4MAOBPPARGPPARA | |
| SCHEMBL18571362 | 0.80 | CYP3A4 (0.61) | CYP3A4MAOBALOX5 | |
| SCHEMBL7556111 | 0.80 | PPARG (0.58) | MAOBPTPN1PPARGPPARA | |
| SCHEMBL7556849 | 0.79 | MAOB (0.52) | MAOBPTPN1 | |
| SCHEMBL7550529 | 0.78 | PTPN1 (0.50) | CYP3A4MAOBPTPN1PPARG | |
| SCHEMBL11663421 | 0.78 | PPARG (0.65) | MAOBPPARGPPARA | |
| SCHEMBL18571363 | 0.76 | CYP3A4 (0.59) | CYP3A4MAOBALOX5HPGDS | |
| SCHEMBL20377546 | 0.76 | MAOB (0.76) | MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1071333-C | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1170411-A | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |